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Takashi Nakano Selected Research

Malignant Mesothelioma

1/2022Phase I Study of Tremelimumab Monotherapy or in Combination With Durvalumab in Japanese Patients With Advanced Solid Tumors or Malignant Mesothelioma.
1/2022Neoadjuvant pemetrexed plus cisplatin followed by pleurectomy for malignant pleural mesothelioma.
6/2021Bevacizumab plus cisplatin/pemetrexed then bevacizumab alone for unresectable malignant pleural mesothelioma: A Japanese safety study.
2/2020Mesothelioma developing in carriers of inherited genetic mutations.
11/2019The mTOR Signaling Pathway Is Associated With the Prognosis of Malignant Pleural Mesothelioma After Multimodality Therapy.
1/2019Targeting angiogenesis for patients with unresectable malignant pleural mesothelioma.
1/2019Maintenance Defactinib Versus Placebo After First-Line Chemotherapy in Patients With Merlin-Stratified Pleural Mesothelioma: COMMAND-A Double-Blind, Randomized, Phase II Study.
1/2019Prediction modelling using routine clinical parameters to stratify survival in Malignant Pleural Mesothelioma patients undergoing cytoreductive surgery.
1/2019Nintedanib in combination with pemetrexed and cisplatin for chemotherapy-naive patients with advanced malignant pleural mesothelioma (LUME-Meso): a double-blind, randomised, placebo-controlled phase 3 trial.
1/2019Pleural thickness after neoadjuvant chemotherapy is a prognostic factor in malignant pleural mesothelioma.
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Takashi Nakano Research Topics

Disease

179Neoplasms (Cancer)
07/2022 - 09/2002
71Malignant Mesothelioma
01/2022 - 09/2006
58Uterine Cervical Neoplasms (Cancer of the Cervix)
03/2022 - 12/2005
32Prostatic Neoplasms (Prostate Cancer)
07/2022 - 06/2004
30Squamous Cell Carcinoma (Epidermoid Carcinoma)
03/2022 - 09/2003
30Lung Neoplasms (Lung Cancer)
01/2022 - 08/2007
27Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
06/2021 - 01/2004
25Mesothelioma
01/2022 - 01/2008
25Carcinoma (Carcinomatosis)
01/2022 - 02/2003
19Hepatocellular Carcinoma (Hepatoma)
08/2020 - 05/2010
18Adenocarcinoma
01/2022 - 09/2004
14Neoplasm Metastasis (Metastasis)
04/2021 - 10/2004
13Infections
08/2021 - 08/2002
10Melanoma (Melanoma, Malignant)
01/2022 - 11/2010
10Human Influenza (Influenza)
10/2021 - 11/2009
10Hypoxia (Hypoxemia)
05/2021 - 11/2002
10Esophageal Neoplasms (Esophageal Cancer)
01/2019 - 11/2003
10Rectal Neoplasms (Rectal Cancer)
01/2019 - 01/2004
8Stomach Neoplasms (Stomach Cancer)
01/2022 - 02/2008
8Necrosis
10/2017 - 07/2013
7Adenocarcinoma of Lung
01/2022 - 02/2003
7Pneumonia (Pneumonitis)
01/2018 - 07/2003
7Brain Neoplasms (Brain Tumor)
09/2015 - 01/2006
6Disease Progression
06/2021 - 05/2011
6Hyperthermia
10/2018 - 09/2005
6Hemorrhage
09/2018 - 11/2004
6Whooping Cough (Pertussis)
01/2018 - 02/2015
6Pulmonary Fibrosis (Fibrosing Alveolitis)
01/2016 - 07/2007
6Pleural Effusion (Pleural Effusions)
12/2015 - 01/2011
5Fever (Fevers)
12/2021 - 02/2006
5Pancreatic Neoplasms (Pancreatic Cancer)
06/2021 - 01/2018
5Lymphatic Metastasis
01/2020 - 05/2007
5Poliomyelitis (Polio)
01/2018 - 06/2004
5Carcinogenesis
01/2017 - 08/2005
5Inflammation (Inflammations)
04/2016 - 08/2013
5Glioblastoma (Glioblastoma Multiforme)
09/2015 - 08/2008
5Esophageal Squamous Cell Carcinoma
08/2012 - 07/2005
4Gastroenteritis
12/2021 - 10/2016
4Sarcoma (Soft Tissue Sarcoma)
05/2021 - 12/2014
4Mucositis
12/2019 - 11/2005
4Colorectal Neoplasms (Colorectal Cancer)
03/2018 - 05/2010
4Asbestosis
04/2010 - 10/2006
4Fibrosis (Cirrhosis)
01/2010 - 03/2006
3Endometrial Neoplasms (Endometrial Cancer)
01/2022 - 01/2011
3Colonic Neoplasms (Colon Cancer)
01/2022 - 01/2010
3Cough
08/2021 - 01/2017
3Mycoplasma Pneumonia
02/2021 - 08/2013
3Stress Fractures (Stress Fracture)
01/2021 - 01/2010
3Urinary Bladder Neoplasms (Bladder Cancer)
05/2020 - 01/2012
3Glioma (Gliomas)
04/2020 - 01/2010

Drug/Important Bio-Agent (IBA)

42CarbonIBA
07/2022 - 04/2006
29Cisplatin (Platino)FDA LinkGeneric
01/2022 - 11/2005
28AsbestosIBA
02/2020 - 09/2006
20Proteins (Proteins, Gene)FDA Link
05/2021 - 09/2004
18DNA (Deoxyribonucleic Acid)IBA
07/2022 - 01/2003
15Biological ProductsIBA
07/2022 - 01/2004
14VaccinesIBA
11/2022 - 06/2004
12Pemetrexed (MTA)FDA Link
01/2022 - 03/2008
9Adenosine (Adenocard)FDA LinkGeneric
08/2012 - 04/2010
8Caspase 3 (Caspase-3)IBA
03/2013 - 01/2009
7Biomarkers (Surrogate Marker)IBA
06/2021 - 02/2009
7CytokinesIBA
04/2015 - 07/2007
7Purinergic P1 Receptors (Adenosine Receptor)IBA
08/2012 - 04/2010
6Pharmaceutical PreparationsIBA
12/2021 - 01/2014
6Anti-Bacterial Agents (Antibiotics)IBA
01/2021 - 05/2013
6IonsIBA
09/2019 - 02/2008
6ChromatinIBA
08/2017 - 12/2006
5AndrogensIBA
07/2022 - 09/2008
5AntigensIBA
01/2022 - 08/2012
5MacrolidesIBA
02/2021 - 05/2013
5Indicators and Reagents (Reagents)IBA
11/2020 - 01/2004
5MesothelinIBA
12/2017 - 01/2008
5naftopidilIBA
11/2016 - 01/2013
5Paclitaxel (Taxol)FDA LinkGeneric
01/2016 - 02/2003
5CaspasesIBA
11/2015 - 01/2009
4Messenger RNA (mRNA)IBA
01/2022 - 01/2011
4laninamivirIBA
10/2021 - 06/2013
4Oseltamivir (Tamiflu)FDA Link
08/2021 - 12/2013
4HMGB1 Protein (HMG1)IBA
09/2018 - 04/2013
4EnzymesIBA
09/2018 - 05/2002
4Oxygen (Dioxygen)IBA
03/2018 - 11/2002
4SteroidsIBA
01/2017 - 04/2014
4Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2017 - 07/2007
4Carboplatin (JM8)FDA LinkGeneric
11/2016 - 02/2012
3Monoclonal AntibodiesIBA
01/2022 - 01/2012
3Bevacizumab (Avastin)FDA Link
06/2021 - 11/2016
3Amino Acid Transport Systems (Amino Acid Transporter)IBA
03/2021 - 10/2010

Therapy/Procedure

139Radiotherapy
03/2022 - 09/2002
103Heavy Ion Radiotherapy
01/2022 - 06/2006
71Therapeutics
07/2022 - 01/2003
40Brachytherapy
03/2022 - 01/2004
32Drug Therapy (Chemotherapy)
05/2020 - 01/2006
18Chemoradiotherapy
05/2020 - 07/2005
7Immunotherapy
01/2022 - 03/2015
7Aftercare (After-Treatment)
04/2021 - 11/2008
6Intensity-Modulated Radiotherapy (Radiotherapy, Intensity Modulated)
01/2020 - 01/2012
6Pneumonectomy (Lung Volume Reduction)
11/2019 - 03/2009
5Cytoreduction Surgical Procedures
01/2019 - 08/2011
4Conservative Treatment
12/2019 - 06/2017
4Conformal Radiotherapy
07/2017 - 08/2010